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Mechanism

Retatrutide is a triple agonist of GLP-1, GIP, and glucagon receptors. It reduces appetite, increases energy expenditure, and improves metabolic function simultaneously — outperforming dual-agonists in clinical trials.

Typical Research Protocol

• Starting dose: 0.5–1mg weekly
• Titration: increase by 0.5mg every 4 weeks
• Maintenance: 4–8mg weekly (subject-dependent)
• Reconstitute with bacteriostatic water

Storage

Store lyophilised powder at 2–8°C. After reconstitution, refrigerate and use within 28 days. Do not freeze reconstituted solution.

Mechanism

BPC-157 is a pentadecapeptide derived from human gastric juice. It upregulates growth hormone receptors, accelerates angiogenesis, and modulates nitric oxide production — promoting healing in tendons, ligaments, gut lining, and muscle tissue.

Typical Research Protocol

• Dosing: 250–500mcg twice daily
• Systemic or localised subcutaneous injection
• Cycle length: 4–12 weeks depending on indication
• Reconstitute with bacteriostatic water

Storage

Store lyophilised powder at −20°C for long-term or 4°C short-term. Reconstituted solution stable at 4°C for up to 14 days.

Mechanism

Ipamorelin selectively binds ghrelin receptors in the pituitary, triggering pulsatile GH release without stimulating cortisol, prolactin, or ACTH — making it one of the cleanest GH secretagogues in research.

Typical Research Protocol

• 200–300mcg injected 2–3× daily
• Best administered fasted or before sleep
• Commonly stacked with CJC-1295 for amplified effect
• Cycle: 8–12 weeks

Storage

Store powder at −20°C long-term. Reconstituted solution stable at 4°C for 14–21 days. Keep away from light.

Mechanism

Melanotan II activates MC1R and MC4R receptors, stimulating melanin production and darkening the skin. It works synergistically with UV light, allowing a deeper tan with significantly less sun exposure.

Typical Research Protocol

• Loading: 0.25–0.5mg subcutaneously daily for 1–2 weeks
• Maintenance: 0.5–1mg every 2–3 days
• Administer 30–60 min before UV exposure
• Reconstitute with bacteriostatic water

Storage

Store lyophilised at 4°C or −20°C for long-term storage. Reconstituted solution: refrigerate and use within 30 days. Protect from light.

Mechanism

PT-141 acts centrally on MC3R and MC4R receptors in the hypothalamus, triggering dopamine-driven sexual arousal — distinct from PDE5 inhibitors which act peripherally. Effective in both male and female subjects in clinical research.

Typical Research Protocol

• Dose: 1–2mg subcutaneously
• Administer 30–60 min before activity
• Effects last 6–12 hours
• Do not exceed 1–2 uses per week

Storage

Store lyophilised powder at 4°C. Reconstituted with bacteriostatic water, stable for 28 days at 4°C. Keep away from heat and direct light.